Female
Hormone Panel (FHP)
For most women, hormone therapy is a very "one size
fits all" proposition. This is simply inappropriate
due to the varied nature among women, natural cyclical hormone
changes and the need for more frequent sampling to properly
quantify hormone levels present.
Often only a single blood sample is taken to assess hormone
levels. It has been shown for example, that a single sample
on day 20-22 of a cycle is less than 50% accurate. That's
one of the many reasons I have chosen to use the FHP: it
remedies this shortcoming by using a schedule for 11 samples
distributed over a complete cycle - start to finish.
The FHP includes 11 Estradiol (E2) and 11 Progesterone
(P) measurements, cycle average DHEA and Testosterone, 3
Progesterone production indices, 4 Estradiol production
indices, a full cycle P/E ratio graph and an example of
a restorative plan.
I find that these values are just as important as any other
value that we obtain each year such as our cholesterol number
or anything else.
Hormones affect more than we might initially believe. They
are powerful, present and there to work for you not against
you.
Arm yourself with the most information possible by reading
through this website and then make the decision for yourself
about whether you think that it's important to include this
testing at the same time that you complete your annual exam.
It's that important. I hope you'll agree.
Expanded Female Hormone Panel
(eFHP)
This panel includes all of the tests of the FHP with the
addition of 5 LH and FSH measurements to see if brain control
and stimulation of the ovaries is optimal. I commonly use
this test to assess women with fertility issues.
There should be links for the following:
Who should consider a Female Hormone Panel?
This particular test is most applicable to cycling women
experiencing the following:
*Weight gain
*Functional infertility
*Osteoporosis
*Endometriosis & ovarian systs
*Fibroids & fibrotic breasts
*Increased risk of breast cancer
*Recurrent cycle related symptoms & irregularities such
as PMS, migraine headaches, breast tenderness, emotional
& cognitive issues, spotting, etc.
How does the FHP assess the
risk for breast & uterine diseases?
It is universally accepted that there is an increased risk
for proliferative diseases in the breast and endometrial
tissues when estrogen is overly dominant. The FHP and eFHP
panels include the Follicular Estrogen Priming Index that
quantifies the impact of excessive estradiol in cycling
women.
It should be known that certain estrogen metabolites have
been and are falsely promoted as risk markers for breast
cancer. A study, which compared 2/16 Hydroxyestrone ratio
in women with breast cancer to a control group of cancer-free
women, concluded that there is no support for the hypothesis
that the ratio 2/16 Hydroxyestrone is an important risk
factor for breast cancer.
(J Nat'l Cancer Inst 1999 Jun 16:91(12):1067-72)
What are the ADVANTAGES of
the FHP & eFHP?
1. Convenience: There are no blood draws required and no
repeat visits to the lab necessary. You receive one kit
and complete it on your own. You are also able to avoid
the inconvenience of the 24-hour urine collection.
2. Economy: The fee for the 11-sample test is less than
that of 2 blood determinations or a urine analysis for estrogen
& progesterone only.
3. Physiological Accuracy: Research has demonstrated that
the free hormone fraction predominates in saliva. Hormones
can be found free or bound to protein. The free hormone
fraction is very important to ascertain because it is the
bioactive fraction that most significantly influences live
cells. The salivary female hormone levels correlate at 93%
with the free hormones in the tissues. One or two blood
tests or a 24-hour urine analysis cannot give an idea of
the ovaries' hormonal productivity. The FHP gives a good
approximation of the ovarian capacity over a whole cycle.
4. Detection of Luteal Phase Defects: There are three luteal
phase defect patterns characterized by a reduction in progesterone
leading to estrogen dominance. This imbalance is associated
with PMS, infertility, fibroids and other female hormone
issues that can be readily detected by these panels.
5. Detection of Specific Hormonal Imbalance: Many women
suffer from hormone imbalance but pursue treatment in a
"one size fits all" package. This test allows
for the specific and individual assessment of a woman's
hormonal state.
6. Customized Hormone Therapy: Currently hormone therapy
will frequently not address the specific issues present
in a woman and consequently most women are generally treated
without regard to their own needs. These panels allow the
clinician to customize treatment options to each female
patient.
What do you know about ESTROGEN?
Estrogen has many vitals roles that it plays in a woman's
body. Although often vilified, it is a very necessary component
to overall health when present in the correct proportions.
For a brief overview, please
read the following:
Reproductive
*Aids in endometrial growth & proliferation
*Aids in inducing ovulation
*Aids in maintaining vaginal lubrication
Central Nervous System
*Neuroprotective
*Neuroexcitatory, motivational & promotes territorial
instincts
*Exacerbates migraine & other headaches
Sexuality
*Estrogen/progesterone balance promotes arousability
Growth
*Increases growth hormone secretion
Bone Health
*Limits bone elongation in adolescents & prevents bone
loss in adults
Glycemic Regulation
*Improves insulin factors
Adipose Tissue
*Increases the size & number of fat cells
Immune System
*Immune activator & pro-inflammatory; estrogen dominance
promotes autoimmunity
Skin
*Maintenance & regeneration
What do you know about PROGESTERONE?
Much of the time so much focus is given to estrogen that
progesterone is left out of the conversation. Frequently
I often see that it is a matter of too much estrogen in
relation to the amount of progesterone present. If related
to the game of basketball for example, it's like having
one team of 5 against a team of 3 during regular court play
when there's a maximum of 5 players allowed on the court.
The team of 3 is going to have to struggle the entire time
just to keep up let alone trying to plan ahead in any way.
This is a situation called "Estrogen Dominance"
and there's a lot that can be done about it. I see it in
women who've taken the birth control pill for even as little
as 1 year and I've seen it in women that haven't ever taken
it at all due to other environmental estrogens that abound
around us.
With respect to fertility issues particularly, many of
the women I've worked with over the years have not been
able to sustain a pregnancy in large part because there
wasn't sufficient progesterone to prevent spontaneous abortion
until the placental progesterone could kick in.
For a brief overview, please
read the following:
Reproductive
*Matures endometrium in preparation for pregnancy
*Facilitates embryo implantation
Maintains pregnancy through maintaining endometrial lining
& preventing uterine muscle contraction
Central Nervous System
*Promotes better sense of dominance, attenuates aggressiveness
& is a sedative
*Promotes neuronal healing (neuroprotective)
Bone Health
*Promotes NEW bone formation & deposition
Sexuality
*Estrogen/progesterone balance promotes arousability; may
play a role in overcoming inhibitions
Breast
*Promotes breast growth & development during pregnancy
*Inhibits lactation during pregnancy
Immunity
*Lowers immune system activity (immunosuppressive)
*Anti-inflammatory
What do you know about DHEA?
For a brief overview, please read the following:
Reproductive
*Integrity of vaginal mucus; eases premenstrual symptoms
Sexuality
*Improves well being & sexual arousability
Antiglucocorticoid Hormone
*Opposes catabolic cortisol effects during stress
Breast
*Reduces breast proliferation
Bone Health
*Enhances bone deposition & remodeling
Glycemic Regulation
*Improves insulin sensitivity, increases muscle mass &
reduces fat mass
Immune System
*Stimulates immune system activity; reverses stress related
immunosuppression
Somatic
*Helps with control of hot flashes & night sweats
*Cardioprotective - reduces the incidence of heart attacks
by lowering total and LDL cholesterol
Anticarcinogenic
*In breast, pancreas, colon & ovaries
What do you know about TESTOSTERONE?
Often thought of in men only, testosterone is vital, particularly
where sexual function is concerned.
For a brief overview, please read the following:
Central Nervous System/Behavioral
*Improves mental faculties including memory & artistic
inclinations
*Excess may lead to aggressive pursuit
Sexuality
*Promotes erotic thoughts & orgasms
Breast
*Reverses estrogen-induced breast proliferation & reduces
breast tenderness
Bone Health
*Helps reduce bone loss & may have a role in bone formation
Glycemic Regulation
*Improves insulin sensitivity & increases muscle mass
Somatic
*Helps attenuate hot flashes & night sweats
Cardiovascular
*Increases blood flow to tissues & may reduce blood
pressure
Immune System
*Immunisuppressor; promotes suppressor T cell dominance
Why are LH & FSH important
to me?
The main purpose of LH & FSH is to regulate ovarian
function. Their origin is the pituitary gland in the brain.
FSH promotes ovarian estrogen production and LH induces
ovulation and progesterone production.
During the time that a woman is in perimenopause, there
are fewer and fewer ovarian follicles. It is then that the
amount of LH and FSH increases dramatically to respond to
this decline.
While in perimenopause FSH is correlated with the following:
*Hot flashes & night sweats
*Bone loss & osteoporosis
*Sleep disturbances
When under a great deal of stress or exercising excessively,
the amount of LH may be affected this inhibiting ovulation.
Stress makes women more estrogenic and less fertile along
with more prone to a host of proliferative diseases.
*Diagnos-Techs, Inc.