Because it is the only way to get an accurate measure of your hormones!

Blood testing is excellent when I want to test your sugar, cholesterol and liver health. But when I want to accurately know what your hormone levels are, saliva is the only way to go because it alone has just active hormones. That's what I need to help you. Blood is a mixture of active and inactive hormones and just confuses the situation. So when you want to restore your hormones to their healty balance, I will be able to help you once I get your saliva test results.

 

Bio-Identical Hormone Replacement Therapy Up Close and Personal, Read More...

Saliva is a valuable diagnosic tool for hormone assesment. Read More....

 

Female Hormone Panel (FHP)

For most women, hormone therapy is a very "one size fits all" proposition. This is simply inappropriate due to the varied nature among women, natural cyclical hormone changes and the need for more frequent sampling to properly quantify hormone levels present.

Often only a single blood sample is taken to assess hormone levels. It has been shown for example, that a single sample on day 20-22 of a cycle is less than 50% accurate. That's one of the many reasons I have chosen to use the FHP: it remedies this shortcoming by using a schedule for 11 samples distributed over a complete cycle - start to finish.

The FHP includes 11 Estradiol (E2) and 11 Progesterone (P) measurements, cycle average DHEA and Testosterone, 3 Progesterone production indices, 4 Estradiol production indices, a full cycle P/E ratio graph and an example of a restorative plan.

I find that these values are just as important as any other value that we obtain each year such as our cholesterol number or anything else.

Hormones affect more than we might initially believe. They are powerful, present and there to work for you not against you.

Arm yourself with the most information possible by reading through this website and then make the decision for yourself about whether you think that it's important to include this testing at the same time that you complete your annual exam.

It's that important. I hope you'll agree.


Expanded Female Hormone Panel (eFHP)

This panel includes all of the tests of the FHP with the addition of 5 LH and FSH measurements to see if brain control and stimulation of the ovaries is optimal. I commonly use this test to assess women with fertility issues.

There should be links for the following:

Who should consider a Female Hormone Panel?

This particular test is most applicable to cycling women experiencing the following:

*Weight gain
*Functional infertility
*Osteoporosis
*Endometriosis & ovarian systs
*Fibroids & fibrotic breasts
*Increased risk of breast cancer
*Recurrent cycle related symptoms & irregularities such as PMS, migraine headaches, breast tenderness, emotional & cognitive issues, spotting, etc.

How does the FHP assess the risk for breast & uterine diseases?

It is universally accepted that there is an increased risk for proliferative diseases in the breast and endometrial tissues when estrogen is overly dominant. The FHP and eFHP panels include the Follicular Estrogen Priming Index that quantifies the impact of excessive estradiol in cycling women.

It should be known that certain estrogen metabolites have been and are falsely promoted as risk markers for breast cancer. A study, which compared 2/16 Hydroxyestrone ratio in women with breast cancer to a control group of cancer-free women, concluded that there is no support for the hypothesis that the ratio 2/16 Hydroxyestrone is an important risk factor for breast cancer.

(J Nat'l Cancer Inst 1999 Jun 16:91(12):1067-72)

What are the ADVANTAGES of the FHP & eFHP?

1. Convenience: There are no blood draws required and no repeat visits to the lab necessary. You receive one kit and complete it on your own. You are also able to avoid the inconvenience of the 24-hour urine collection.
2. Economy: The fee for the 11-sample test is less than that of 2 blood determinations or a urine analysis for estrogen & progesterone only.
3. Physiological Accuracy: Research has demonstrated that the free hormone fraction predominates in saliva. Hormones can be found free or bound to protein. The free hormone fraction is very important to ascertain because it is the bioactive fraction that most significantly influences live cells. The salivary female hormone levels correlate at 93% with the free hormones in the tissues. One or two blood tests or a 24-hour urine analysis cannot give an idea of the ovaries' hormonal productivity. The FHP gives a good approximation of the ovarian capacity over a whole cycle.
4. Detection of Luteal Phase Defects: There are three luteal phase defect patterns characterized by a reduction in progesterone leading to estrogen dominance. This imbalance is associated with PMS, infertility, fibroids and other female hormone issues that can be readily detected by these panels.
5. Detection of Specific Hormonal Imbalance: Many women suffer from hormone imbalance but pursue treatment in a "one size fits all" package. This test allows for the specific and individual assessment of a woman's hormonal state.
6. Customized Hormone Therapy: Currently hormone therapy will frequently not address the specific issues present in a woman and consequently most women are generally treated without regard to their own needs. These panels allow the clinician to customize treatment options to each female patient.


What do you know about ESTROGEN?

Estrogen has many vitals roles that it plays in a woman's body. Although often vilified, it is a very necessary component to overall health when present in the correct proportions.

For a brief overview, please read the following:

Reproductive
*Aids in endometrial growth & proliferation
*Aids in inducing ovulation
*Aids in maintaining vaginal lubrication

Central Nervous System
*Neuroprotective
*Neuroexcitatory, motivational & promotes territorial instincts
*Exacerbates migraine & other headaches

Sexuality
*Estrogen/progesterone balance promotes arousability

Growth
*Increases growth hormone secretion

Bone Health
*Limits bone elongation in adolescents & prevents bone loss in adults

Glycemic Regulation
*Improves insulin factors

Adipose Tissue
*Increases the size & number of fat cells

Immune System
*Immune activator & pro-inflammatory; estrogen dominance promotes autoimmunity

Skin
*Maintenance & regeneration

What do you know about PROGESTERONE?

Much of the time so much focus is given to estrogen that progesterone is left out of the conversation. Frequently I often see that it is a matter of too much estrogen in relation to the amount of progesterone present. If related to the game of basketball for example, it's like having one team of 5 against a team of 3 during regular court play when there's a maximum of 5 players allowed on the court. The team of 3 is going to have to struggle the entire time just to keep up let alone trying to plan ahead in any way.

This is a situation called "Estrogen Dominance" and there's a lot that can be done about it. I see it in women who've taken the birth control pill for even as little as 1 year and I've seen it in women that haven't ever taken it at all due to other environmental estrogens that abound around us.

With respect to fertility issues particularly, many of the women I've worked with over the years have not been able to sustain a pregnancy in large part because there wasn't sufficient progesterone to prevent spontaneous abortion until the placental progesterone could kick in.

For a brief overview, please read the following:

Reproductive
*Matures endometrium in preparation for pregnancy
*Facilitates embryo implantation
Maintains pregnancy through maintaining endometrial lining & preventing uterine muscle contraction

Central Nervous System
*Promotes better sense of dominance, attenuates aggressiveness & is a sedative
*Promotes neuronal healing (neuroprotective)

Bone Health
*Promotes NEW bone formation & deposition

Sexuality
*Estrogen/progesterone balance promotes arousability; may play a role in overcoming inhibitions

Breast
*Promotes breast growth & development during pregnancy
*Inhibits lactation during pregnancy

Immunity
*Lowers immune system activity (immunosuppressive)
*Anti-inflammatory

What do you know about DHEA?

For a brief overview, please read the following:

Reproductive
*Integrity of vaginal mucus; eases premenstrual symptoms

Sexuality
*Improves well being & sexual arousability

Antiglucocorticoid Hormone
*Opposes catabolic cortisol effects during stress

Breast
*Reduces breast proliferation

Bone Health
*Enhances bone deposition & remodeling

Glycemic Regulation
*Improves insulin sensitivity, increases muscle mass & reduces fat mass

Immune System
*Stimulates immune system activity; reverses stress related immunosuppression

Somatic
*Helps with control of hot flashes & night sweats
*Cardioprotective - reduces the incidence of heart attacks by lowering total and LDL cholesterol

Anticarcinogenic
*In breast, pancreas, colon & ovaries

What do you know about TESTOSTERONE?

Often thought of in men only, testosterone is vital, particularly where sexual function is concerned.

For a brief overview, please read the following:

Central Nervous System/Behavioral
*Improves mental faculties including memory & artistic inclinations
*Excess may lead to aggressive pursuit

Sexuality
*Promotes erotic thoughts & orgasms

Breast
*Reverses estrogen-induced breast proliferation & reduces breast tenderness

Bone Health
*Helps reduce bone loss & may have a role in bone formation

Glycemic Regulation
*Improves insulin sensitivity & increases muscle mass

Somatic
*Helps attenuate hot flashes & night sweats

Cardiovascular
*Increases blood flow to tissues & may reduce blood pressure

Immune System
*Immunisuppressor; promotes suppressor T cell dominance

Why are LH & FSH important to me?

The main purpose of LH & FSH is to regulate ovarian function. Their origin is the pituitary gland in the brain.

FSH promotes ovarian estrogen production and LH induces ovulation and progesterone production.
During the time that a woman is in perimenopause, there are fewer and fewer ovarian follicles. It is then that the amount of LH and FSH increases dramatically to respond to this decline.

While in perimenopause FSH is correlated with the following:
*Hot flashes & night sweats
*Bone loss & osteoporosis
*Sleep disturbances

When under a great deal of stress or exercising excessively, the amount of LH may be affected this inhibiting ovulation. Stress makes women more estrogenic and less fertile along with more prone to a host of proliferative diseases.

*Diagnos-Techs, Inc.

Male Hormone Panel

Most people don't consider the hormone health of men, but it must be regarded with respect to three key areas: Vigor, Vitality & Virility.

Problems that concern men in the area of vigor include a loss of a sense of well being, difficulty concentrating, depression, irritability and nervousness along with changes in both behavior and sleep patterns. Loss of vitality presents itself as a decrease in hair density, a reduction in masculinity and an overall decrease in both muscle mass and strength. A decrease in virility can affect both partners as a decline in sexual function and interest, a diminished libido and erectile dysfunction. Although commonly regarded as a woman's issue only, osteoporosis is still a concern for men as a decrease in bone mass can become a problem.

For women there is menopause. For men, andropause. Many men in their fifties or older experience a progressive decline in their energy, sexual performance and mental capacity. It is believe that it is caused by a reduction in testosterone and other androgens. Testicles will show a progressive annual drop of 1-1.5% in testosterone output after age 30. The clinical manifestations of andropause usually lag 20 years behind the onset of hormone decline. Statistically, it will affect at least 40% of men ages 55-65 and up to 80% of those aged 65 years or more.

The Male Hormone Panel is the first salivary test that evaluates the androgen pathway by measuring the free fractions of the following 6 hormones: DHEA, Progesterone, Androstenedione, Estrone, Testosterone and DHT. Knowing the levels of the 6-8 hormones measured in the Male Hormone Panels helps you formulate an effective plan to relieve andropausal symptoms.

Expanded Male Hormone Panel

This panel includes all of the 6 tests in the regular Male Hormone Panel, with the addition of FSH and LH. Salivary quantification of these two hormones is one of the technological breakthroughs that separates Diagnos-Techs from other laboratories.

Testosterone and sperm production in males are the equivalent to estrogen and ovulation in females. As hormones produced by the pituitary, FSH and LH stimulate and regulate these functions in both men and women.

Early detection of an increase in these levels indicates a progressive decline in male sexuality and functionality. Clinically the panel is used to measure baseline hormones for future comparison, assessing andropause and hypogonadism, monitoring HRT, balancing the hormones, investigating prostate hypertrophy, the thinning of hair, hirsutism and low libido.

Frequent Beneficial Effects

Case Study: 58-year old man with progressive fatigue, lack of sexual interest & loss of love for golf

Common Fallacies

Adapted from Diagnos-Techs, Inc.

Long-Term Effects of Topical Progesterone Cream Application: A Case Study

The truth is that hormone levels from woman to woman can vary from 200-1,500%! It's a pretty fantastic range when you really think about it.

With that in mind, consider the fluctuations that might occur when a woman enters the phase of her life when the monthly menstrual cycle ceases and the end of a woman's natural childbearing years have come. Although many might consider "menopause" to be a disease or an illness, it isn't. It's simply a change in glandular function that with proper balance and attention can continue to support a healthful life for decades to come.

Hormones control emotional, mental and physical health. Consider the following areas of endocrine, nervous system and metabolic health:

Endocrine:

  • Bleeding irregularities
  • Vaginal dryness
  • Hot flashes/sweats
  • Changes in sex drive

Nervous System:

  • Insomnia
  • Nervousness/Irritability
  • Headache
  • Mood Changes
  • Depression
Metabolic Changes:
  • Skin aging/cosmetic changes
  • Osteoporosis
  • Altered fat & carbohydrate metabolism
  • Atherosclerosis

What are your choices?

You have many different options to consider when at this particular stage of life. They might include the use of synthetic hormones without any testing, use of synthetic hormones with testing and finally treating and balancing symptoms and hormone levels using specific testing before and after treatment along with natural hormones. If hormones aren't tested before and after treatment then any treatment recommendations are merely an educated guess. If treatment is to be optimized then it needs to be customized.

Review this common example:

A woman suffers from several symptoms - migraines, hot flashes and emotional fragility. She is having irregular periods, one every 6-8 months. Her doctor treats her with natural estrogens, but he does not do any testing to determine quantities or types of hormones to meet her specific needs. The symptoms are under control, but her risks are increased: increased blood pressure; endometrial cancer (uterine cancer); fibroid growth; gallbladder disease and over 15 years, at least twice the risk of breast cancer. The bottom line is that she has too much estrogen and not enough progesterone along with low DHEA and marginal testosterone. While it might be true that she "felt good", as many might say, the silent killers of cancer, blood pressure and heart disease rarely make anyone feel bad from the beginning. Ultimately her best course of treatment would have been, and can still be, a new treatment plan designed around specific, objective saliva hormone measurements.

What's the benefit for a post-menopausal woman in testing?

1. These tests are affordable and less expensive than blood or urine tests. Blood testing for 6 hormones costs $250-$300 more than saliva testing.
2. Collection procedure spares you the pain of venipunctures with a needle.
3. Results are more clinically reflective of your hormone status and needs.
4. Results can lead to an individualized and customized treatment plan using natural hormones.
5. You will minimize overdosing and underdosing. This will insure that you use only the proper hormones in the appropriate amounts.

 

 

Diagnos-Techs, Inc. USA was established in 1987 in Kent, Washington. In 1989, DTI USA introduced salivary-based stress and other hormone assessments into routine clinical practice as a powerful tool in evaluating stress and hormone related diseases and illness. The tests are considered the platinum standard for salivary testing nationwide. Quality control is our primary goal. All parameters on our reports are standardized daily to WHO and other standardization agencies reference materials. This insures continuity of results in follow up tests and permits precise clinical diagnosis based on real values.

Diagnos-Techs has the following goals:

  1. Provide services that result in increased
    well-being for the patients
  2. Use specimens that can be collected by the patient in a non-invasive manner to increase compliance and minimize trauma
  3. Provide high quality laboratory service
  4. Provide education and interpretive support to physicians
  5. Actively pursue a program of research and
    development to continuously improve the
    services that are provided

Licensure and specialties/ Subspecialties:
The laboratory is licensed and inspected by the Washington State Department of Health under the Medical Test Site License program with the biannual renewal. The Washington State License Number is MTS-0327 and the Federal CLIA Number is 50D0630141. The laboratory is licensed in the specialties of Microbiology, Diagnostic immunology and Chemistry. The microbiology subspecialties include bacteriology, mycology and parasitology. Diagnostic immunology includes the subspecialty of general immunology. Chemistry includes the subspecialties of general chemistry and endocrinology.

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